Clinical Bioinformatics Scientist

Company: Labcorp
Location: San Diego
Posted on: July 3, 2025

Job Description:

Imagine being involved with innovative projects that change the course of our industry daily! Labcorp is dedicated to bringing comprehensive genetic information into mainstream medicine to improve healthcare for billions of people. Our Invitae team, now part of Labcorp, is driven to make a difference for the patients we serve. We are leading the transformation of the genetics industry, by making clinical-grade genetic information affordable and accessible to guide health decisions across all stages of life. We have an excellent career opportunity for a Clinical Bioinformatics Scientist to join our growing team. This is a US remote based position. If you have a passion for making quality and data integrity a priority, this is an ideal position for you! Position Summary The Clinical Bioinformatics Scientist is part of a team responsible for the evaluation of the truth of clinically reportable variants and is often required to investigate unique genetic or genomic signals identified in production data. In addition to handling production data, the team is responsible for monitoring data quality metrics and troubleshooting the root cause of quality control failures related to both the mainline Next Generation Sequencing (NGS), Whole Genome Sequencing (WGS), and confirmatory assays. All the team’s work directly impacts patient results, making problem-solving both motivating and rewarding and making quality and data integrity the most important aspects of the role. Preferred Qualifications: Strong knowledge of genetics Experience with NGS data analysis in either an academic or industry environment · Familiarity with IGV or other genome browsers Knowledge of common NGS alignment, variant calling, and visualization tools Familiarity and/or hands-on experience with NGS wet lab protocols, preferably in a production setting but academic knowledge may be sufficient Excellent written and verbal communication skills Familiarity with any of the following: Laboratory Information Management Systems (LIMS) Python, R, SQL, or other programming languages git, GitHub, or other version control systems Project management software such as Jira, Asana, Monday, etc. Essential Duties: Review and assess the veracity of specific genetic variants (SNVs and CNVs) in NGS or WGS data that are flagged for manual intervention. This process entails making decisions that will determine if a variant is reported to a patient or not. Review results from confirmatory assays that corroborate or refute calls made in the primary assay. This can lead to contradictory results between assays where the scientist will need to make the final decision. Troubleshoot quality control anomalies generated by automated pipelines at the sample and/or batch level. Triage stuck samples, variants, and reports. Support other production duties like requests from other teams, production on-call shifts, and program development. Work collaboratively with other teams such as bioinformatics, automation, engineering, clinical genomics, laboratory scientists, laboratory directors, and research scientists in a cross-functional manner. Education/Experience Bachelors degree in a biological field (e.g., biology, microbiology, genetics, genomics, bioinformatics, biochemistry, etc.) and four years of relevant professional experience, minimum requirement. Masters Degree in a biological field (e.g., biology, microbiology, genomics, bioinformatics, biochemistry, etc.) and two years of relevant professional experience preferred. Application window open through: 07/08/2025 Pay Range: $110,000 - $140k (USD) All job offers will be based on a candidate’s skills and prior relevant experience, applicable degrees/certifications, as well as internal equity and market data. The position is also eligible for an annual bonus under the Labcorp Bonus Plan. Bonuses are payable based on corporate and/or business segment performance and are subject to individual performance modifiers Benefits: Employees regularly scheduled to work 20 or more hours per week are eligible for comprehensive benefits including: Medical, Dental, Vision, Life, STD/LTD, 401(k), Paid Time Off (PTO) or Flexible Time Off (FTO), Tuition Reimbursement and Employee Stock Purchase Plan. Casual, PRN & Part Time employees regularly scheduled to work less than 20 hours are eligible to participate in the 401(k) Plan only. For more detailed information, please click here. Why People choose to work at Labcorp: At Labcorp, it is our people that make us great – it is what our clients, our partners and, most importantly, what our employees say. Here, you will have the opportunity to collaborate with extraordinary people with diverse viewpoints. You will discover your own outstanding potential as we build an even stronger organization with industry leaders from early development to the clinic and beyond. We help our clients develop medicines that improve health and improve lives of their family and friends. Labcorp is proud to be an Equal Opportunity Employer: Labcorp strives for inclusion and belonging in the workforce and does not tolerate harassment or discrimination of any kind. We make employment decisions based on the needs of our business and the qualifications and merit of the individual. Qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex (including pregnancy, childbirth, or related medical conditions), family or parental status, marital, civil union or domestic partnership status, sexual orientation, gender identity, gender expression, personal appearance, age, veteran status, disability, genetic information, or any other legally protected characteristic. Additionally, all qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable law. We encourage all to apply If you are an individual with a disability who needs assistance using our online tools to search and apply for jobs, or needs an accommodation, please visit our accessibility site or contact us at Labcorp Accessibility. 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Keywords: Labcorp, Tustin , Clinical Bioinformatics Scientist, Healthcare , San Diego, California