Research Bioinformatician I - Bottini Lab - Kao Autoimmunity Institute

Company: CEDARS-SINAI
Location: Los Angeles
Posted on: May 19, 2025

Job Description:

Job DescriptionData is vital to advance clinical knowledge across a spectrum of medical and surgical fields. Are you ready to transform data discoveries into valuable information, which will empower tomorrow's medicine? We invite you to consider and apply to this great opportunity today!Principal Investigator, Nunzio Bottini, MD, PhD invites you to consider this great opportunity to join his dynamic team!The Kao Autoimmunity Institute was established as a vital hub where investigators with experience in clinical, translational, and basic research can collaborate to advance our understanding of pathways to disease and disease expression. The Bottini Lab studies the pathogenesis of systemic autoimmunity, with a particular focus on scleroderma and rheumatoid arthritis. The key goal is to identify avenues for treatments of systemic autoimmunity that would be more effective and personalized while minimizing or avoiding generalized immunosuppression.The Research Bioinformatician I will perform general bioinformatics analysis and software support for projects involving in omics. The RB I member will manage omic data including loading and querying data from database systems and public repositories, and transforms and merges multilevel omic data into user-friendly formats. The incumbent assists in development, testing, and maintenance of modular software pipelines for genome sequencing, provides daily bioinformatics data analysis, preliminary interpretation of the data, and reports of the results for possible publications.Primary Job Duties and Responsibilities:

• Responsible for data analysis and software compilations including next generation sequence alignment, polymorphism identification, expression analysis, and visualization tools and browsers.
• Summarizes data analyses results in the form suitable as the basis for the first draft of written reports, and makes preliminary interpretations of the data.
• Assists with assembly, annotation, meta-genomic analysis, and genotyping using high-throughput sequencing platforms including 454, Illumina, and Pacific Biosciences.
• Manages and redefines data to the necessary formats.
• Helps to identify, evaluate, and incorporate relevant algorithms and software pipelines by reviewing pertinent literatures in bioinformatics and computational biology.
  QualificationsEducation:
  • Bachelor's Degree in Computer Science, Electrical Engineering, Computational Biology, Bioinformatics, or relevant fields (e.g., Biology with strong quantitative training, Biostatistics with concentration in Bioinformatics) is required.Experience:
    • Experience in a research environment is highly preferred.
    • Background and work knowledge in algorithms, scientific computing, and machine learning or statistics is preferred.
    • Proficiency with C/C++, Java, Perl, python, and the Unix (Linux) environment is a plus.
    • Experience in manipulating, analyzing, and annotating very large genomic (e.g. NGS) data sets, both in exploratory and pipelined fashions is highly preferred.
      About UsCedars-Sinai is a leader in providing high-quality healthcare encompassing primary care, specialized medicine and research. Since 1902, Cedars-Sinai has evolved to meet the needs of one of the most diverse regions in the nation, setting standards in quality and innovative patient care, research, teaching and community service. Today, Cedars- Sinai is known for its national leadership in transforming healthcare for the benefit of patients. Cedars-Sinai impacts the future of healthcare by developing new approaches to treatment and educating tomorrow's health professionals. Additionally, Cedars-Sinai demonstrates a commitment to the community through programs that improve the health of its most vulnerable residents.
      About the TeamCedars-Sinai is one of the largest nonprofit academic medical centers in the U.S., with 886 licensed beds, 2,100 physicians, 2,800 nurses and thousands of other healthcare professionals and staff. Choose this if you want to work in a fast-paced environment that offers the highest level of care to people in the Los Angeles that need our care the most.
      Req ID : 8950
      Working Title : Research Bioinformatician I - Bottini Lab - Kao Autoimmunity Institute
      Department : Research - Rheumatology
      Business Entity : Cedars-Sinai Medical Center
      Job Category : Academic / Research
      Job Specialty : Bioinformatics
      Overtime Status : EXEMPT
      Primary Shift : Day
      Shift Duration : 8 hour
      Base Pay : $34.24 - $58.21

Keywords: CEDARS-SINAI, Tustin , Research Bioinformatician I - Bottini Lab - Kao Autoimmunity Institute, Healthcare , Los Angeles, California