Executive Director, Disease Area Strategy Lead, Obesity and Related Conditions

Company: Amgen
Location: Thousand Oaks
Posted on: February 7, 2026

Job Description:

At Amgen, if you feel like you are a part of something bigger, its because you are. Our shared missionto serve patients living with serious illnessesdrives all that we do.Since 1980, weve helped pioneer the world of biotech in our fight against the worlds toughest diseases. With our focus on four therapeutic areas Oncology, Inflammation, General Medicine, and Rare Disease we reach millions of patients each year. As a member of the Amgen team, youll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, youll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Live What you will do Lets do this. Lets change the world. As we increase our investment in discovery research and early pipeline development, this role is critical to drive commercial strategy at the earliest stages of innovation. This position requires a leader who understands the intersection of science, strategy, and commercial executionensuring that Amgens early-stage investments are positioned for long-term success. TheExecutive Director (ED), Disease Areas Strategy Lead (DASL) for OaR will play a pivotal role in shaping the future of Amgens portfolio by providing commercial insights into early-stage research, pipeline programs, and external business development opportunities. In this role you will be responsible for the following : Partnering with Senior Leadership to define Amgens early pipeline commercial strategyto ensure investments in research and early development align with long-term business objectives and patient needs within OaR Partnering closely with R&D, global marketing, and corporate development teamsto assess external innovation and business development opportunities, ensuring alignment with Amgens portfolio strategy Supporting portfolio investment decisions in coordination with theEnterprise Portfolio Governance function Developing commercial frameworks and business casesto inform progression decisions for early-stage assets, integrating insights from market dynamics, patient needs, and competitive intelligence Building a best-in-class commercial function for early pipeline strategy, ensuring Amgen maintains a leadership position in bringing first-in-class and best-in-class therapies to market Key activities and accountabilities include the following : Early Pipeline Strategy & Portfolio Prioritization Leverages frameworks for evaluating and prioritizing early-stage assets Assess commercial viability and differentiation of assets in early development, ensuring alignment with evolving market needs and payer landscapes Shape long-term portfolio strategy in collaboration with R&D, finance, and business development teams Commercial Partnership with Research & Early Development Provide commercial input to research-stage investment decisions, ensuring a clear path to differentiated and commercially viable products Collaborate with R&D to developtarget product profiles (TPPs)that reflect strong commercial positioning Business development & External Innovation Partner with Amgens Business Development team to evaluate in-licensing, partnerships, and acquisitions for early-stage assets Conduct commercial due diligence on external opportunities, integrating scientific innovation with market insights Leadership & Team Development Lead the cross functional Therapy Area Strategy group focused on early pipeline and business development Establish strong cross-functional partnerships with R&D, corporate strategy, finance, and global marketing teams Enterprise Portfolio Governance & Investment Strategy Play a key role in thePortfolio Governance process, ensuring that commercial insights drive R&D investment decisions Align early-stage investments with Amgens strategic growth objectives and therapeutic area priorities Win What we expect of you We are all different, yet we all use our unique contributions to serve patients. The professional we seek is a leader with these qualifications. Basic Qualifications: Doctorate degree & 6 years of commercial experience OR Masters degree & 10 years of commercial experience OR Bachelors degree & 12 years of commercial experience AND 6 years of managerial experience directly managing people and/or leadership experience leading teams, projects, programs or directing the allocation of resources A minimum of 3 years of relevant experience either via a scientific degree or position held in a scientific field Preferred Qualifications: Master of Business Administration MD or PhD in a life sciences-related field (e.g., molecular biology, immunology, pharmacology) 12 years of commercial experience in the biopharmaceutical industry, with time spent in marketing, commercial strategy, and/or pipeline development Experience inmanagement consulting(McKinsey, Bain, BCG) focused on strategy, commercial development, and business development in the life sciences industry Experience incommercial development for pipeline assets, including product positioning, market assessment, and competitive analysis Experience inbusiness development, including due diligence and partnership evaluations Experience working in cross-functional leadership roles across commercial and R&D teams Track record inenterprise portfolio strategy, including investment decision-making and pipeline prioritization Executive leadership and people management skills with a proven ability to develop and mentor high-performing teams Priorbiopharmaceutical leadership experienceoverseeing commercial strategy, commercial development, and marketing functions Deep knowledge of global biopharma market dynamics, payer trends, and competitive landscapes Experience engaging withexecutive leadership and board-level stakeholderson commercial and R&D investment decisions Analytical, financial, and strategic thinking skills with the ability to translate complex data into actionable insights Thrive What you can expect of us As we work to develop treatments that take care of others, we also work to care for our teammates professional and personal growth and well-being. The annual base salary range for this opportunity in the U.S. $315,211 to $362,906. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan Stock-based long-term incentives Award-winning time-off plans and bi-annual company-wide shutdowns Flexible work models, including remote work arrangements, where possible As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease. Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.Sponsorship is not guaranteed for this role.

Keywords: Amgen, Tustin , Executive Director, Disease Area Strategy Lead, Obesity and Related Conditions, Accounting, Auditing , Thousand Oaks, California